It has strong estrogenic properties, and as a result is the most important element when nutritionally treating menopausal symptoms, menstrual problems, osteoporosis, and postpartum depression, for which manganese, along with Vitamin B1, is most effective. Manipulating manganese levels can be an effective way to delay, or hasten menopause, trigger the menstrual cycle again after starting menopause, or along with iron and iodine levels, affect the frequency, duration and heaviness of the menstrual cycle... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...